A quarter of the pier at Fisherman’s Wharf “has been lost to the flames,” according to the San Francisco Fire Department public information officer.
No injuries have been reported. The pier has been fully evacuated, the department says.
Flames could be seen in the early morning darkness in photos tweeted by Dan Whaley.
The blaze was first reported at 4:17 a.m. local time (7:17 a.m. ET) and has been contained to a section of the pier.
The Fire Department tweeted a link to live updates.
Officers report the fire caused a partial building collapse on the southern part of the pier, spread to two buildings on the pier and is in danger of spreading to a third, the Fire Department says.
There is no word yet of a cause.
Fireboat St. Francis was put in position to protect the historic SS Jeremiah O’Brien ship built during World War II, and it successfully saved the ship from damage, said Jonathan Baxter, the department’s spokesman.
Several fireboats are positioned around the wharf and helping fight the fire.
The warehouse contained a large fish processing operation for the Northern California crab fleet, KPIX reports.